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John M D Storey Selected Research

hydromethylthionine

4/2022HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine.
1/2020Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia.
1/2019Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer's Disease.
10/2018Cysteine-Independent Inhibition of Alzheimer's Disease-like Paired Helical Filament Assembly by Leuco-Methylthioninium (LMT).
1/2018Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer's Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial.
1/2017A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy.

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John M D Storey Research Topics

Disease

12Alzheimer Disease (Alzheimer's Disease)
04/2022 - 04/2014
4Atrophy
04/2022 - 01/2018
3Tauopathies
04/2022 - 04/2015
2Cognitive Dysfunction
04/2022 - 01/2019
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018 - 01/2017
1Frontotemporal Dementia (Semantic Dementia)
01/2020
1Synucleinopathies
01/2017
1Parkinson Disease (Parkinson's Disease)
01/2017

Drug/Important Bio-Agent (IBA)

6hydromethylthionineIBA
04/2022 - 01/2017
5tau Proteins (tau Protein)IBA
04/2022 - 04/2015
2Pharmaceutical PreparationsIBA
01/2020 - 01/2018
2Proteins (Proteins, Gene)FDA Link
11/2017 - 01/2017
2Amyloid (Amyloid Fibrils)IBA
11/2017 - 06/2015
1Rivastigmine (Exelon)FDA LinkGeneric
04/2022
1Cysteine (L-Cysteine)FDA Link
10/2018
1PrionsIBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2018
1DisulfidesIBA
11/2017
1SynucleinsIBA
01/2017
1Methylene Blue (Methylthioninium Chloride)FDA Link
12/2016

Therapy/Procedure

8Therapeutics
04/2022 - 04/2014
2Activities of Daily Living (ADL)
01/2018 - 12/2016